Novavax Covid-19 vaccine shows 43 percent efficacy against South African variant
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New Delhi: Novavax Inc's Covid-19 vaccine had efficacy of 43% against infections caused by the South African variant in a group that included people with and without HIV, and 51% in people who were HIV negative, according to a new analysis published on Wednesday.
The post-hoc analysis was published in the New England Journal of Medicine along with full data from the company's trial in South Africa, which included nearly 2,700 volunteers who had not been previously infected with the coronavirus.
The trial's main goals were to test how the vaccine performed in people who were HIV negative, as well as those who were HIV positive and medically stable. The study excluded other volunteers taking drugs to suppress the immune system or those with auto-immune diseases, which could reduce vaccine efficacy. Among those evaluated, 94% were HIV negative and 6% were HIV positive.
Novavax has said it is making new versions of its vaccine to protect against emerging virus variants. The company is expected to report data from its ongoing late-stage study in the United States and Mexico in the second quarter.
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