NPPA Revises Ceiling Prices of 138 Essential Drugs with WPI-Linked Hike Effective April 1

Written By :  Susmita Roy
Published On 2026-04-02 13:47 GMT   |   Update On 2026-04-02 13:47 GMT

New Delhi: Through a recent notification, the National Pharmaceutical Pricing Authority (NPPA), under the Ministry of Chemicals and Fertilizers, Government of India, has revised the ceiling prices of 138 scheduled drug formulations based on the annual Wholesale Price Index (WPI) adjustment under the provisions of the Drugs (Prices Control) Order, 2013.

The price revision reflects a marginal increase of 0.64956% for the year 2025 over 2024, and the revised ceiling prices will come into effect from April 1, 2026. The formulations span a wide range of essential therapeutic categories, including anti-retrovirals, antibiotics, analgesics, vaccines, oncology drugs, cardiovascular medicines, and intravenous fluids.

Key formulations include Abacavir and Lamivudine Tablets (Rs. 25.61 per tablet), Acetylsalicylic Acid Tablets (starting from Rs. 0.21 per tablet depending on strength), Anti-D Immunoglobulin Injection (Rs. 2721.28 per pack), Artesunate-based anti-malarial combination packs (ranging from Rs. 25.07 to Rs. 51.05 per pack), Benzoyl Peroxide Cream (Rs. 2.97 per gm), Cefixime Capsules (Rs. 37.28 per capsule), Coagulation Factor VIII Injection (up to Rs. 11,685.13 per pack), and Temozolomide Tablets (Rs. 1971.83 per tablet), among others.

The notification stated,

"In exercise of the powers, conferred by paragraph 4, 6, 10, 11, 14, 16, 17 and 18 of the Drugs (Prices Control) Order, 2013, read with S.O. No. 1394(E) dated 30th May, 2013, 5249(E) dated 11th November, 2022 issued by the Government of India in the Ministry of Chemicals and Fertilizers, and in supersession of the Order(s) of the Government of India in the Ministry of Chemicals and Fertilizers (National Pharmaceutical Pricing Authority) S.O. Number and date specified in column no. 6(a) & 6(b) mentioned in the table below, the National Pharmaceutical Pricing Authority, hereby fixes the prices as specified in column (5) of the table herein below as ceiling prices exclusive of Goods and Services Tax applicable, if any, in respect of the Scheduled formulations specified in the corresponding entry in column (2) of the said Table with the dosage form & strength and unit specified respectively in the corresponding entries in columns (3) and (4) thereof:

Sl.

No.

Medicines

Dosage form and strength

Unit

Ceiling price (w.e.f.

1.4.2026

with WPI @ 0.64956%)

(in Rs.)

Existing S.O., No. & Date

(1)

(2)

(3)

(4)

(5)

(6a)

(6b)

1

Abacavir (A) + Lamivudine (B)

Tablet 60 mg(A) + 30 mg(B)

1 Tablet

25.61

1487(E)

27-03-2025

2

Acetylsalicylic acid

Effervescent/ Dispersible/ Enteric coated Tablet 100 mg

1 Tablet

0.22

1487(E)

27-03-2025

3

Acetylsalicylic acid

Tablet 100 mg

1 Tablet

0.21

1487(E)

27-03-2025

4

Acetylsalicylic acid

Tablet 350mg

1 Tablet

0.39

1487(E)

27-03-2025

5

Acetylsalicylic acid

Tablet 75 mg

1 Tablet

0.39

1487(E)

27-03-2025

6

Acetylsalicylic acid

Tablet 150 mg

1 Tablet

0.51

1487(E)

27-03-2025

7

All-trans Retinoic Acid

Capsule 10 mg

1 Capsule

104.29

1487(E)

27-03-2025

8

Anti-D immunoglobulin

Injection 300mcg

Each Pack

2721.28

1487(E)

27-03-2025

9

Anti-D Immunoglobulin

Injection 150mcg

Each Vial

2121.14

1487(E)

27-03-2025

10

Artesunate (A) + Sulphadoxine - Pyrimethamine (B)

1 Tablet 100 mg(A) + 1 Tablet (750 mg+ 37.5

mg) (B)

Combi pack

37.60

1487(E)

27-03-2025

11

Artesunate (A) + Sulphadoxine - Pyrimethamine (B)

1 Tablet 150 mg(A) + 2 Tablet (500 mg+ 25 mg) (B)

Combi pack

51.05

1487(E)

27-03-2025

12

Artesunate (A) + Sulphadoxine - Pyrimethamine (B)

1 Tablet 200 mg(A) + 2 Tablet (750 mg+ 37.5

mg) (B)

Combi pack

46.54

1487(E)

27-03-2025

13

Artesunate (A) + Sulphadoxine - Pyrimethamine (B)

1 Tablet 25 mg(A)

+ 1 Tablet (250 mg+ 12.5 mg) (B)

Combi pack

25.07

1487(E)

27-03-2025

14

Benzoyl Peroxide

Cream 2.5%

1 gm

2.97

1487(E)

27-03-2025

15

Benzyl penicillin

Powder for Injection 10 Lac Units

Each Pack

14.92

1487(E)

27-03-2025

16

Betamethasone

Lotion 0.1%

1 ml

1.05

1487(E)

27-03-2025

17

Budesonide

Nasal Spray 50 mcg/dose

1 Dose

1.30

1487(E)

27-03-2025

18

Budesonide

Inhalation (DPI) 100 mcg/dose

1 Dose

2.55

1487(E)

27-03-2025

19

Calcium Carbonate

Tablet 500mg

1 Tablet

2.20

1487(E)

27-03-2025

20

Calcium gluconate

Injection 100

mg/ml

1 ml

0.69

1487(E)

27-03-2025

21

Cefadroxil

Capsule 500 mg

1 Capsule

9.11

1487(E)

27-03-2025

22

Cefazolin

Powder for Injection 1 gm

Each Pack

31.29

1487(E)

27-03-2025

23

Cefazolin

Powder for Injection 500 mg

Each Pack

19.84

1487(E)

27-03-2025

24

Cefixime

Capsule 400 mg

1 Capsule

37.28

1487(E)

27-03-2025

25

Cetirizine

Capsule 10 mg

1 Capsule

3.03

1487(E)

27-03-2025

26

Chlorhexidine

Solution 5% (Concentrate for dilution)

1 ml

0.19

1487(E)

27-03-2025

27

Cloxacillin

Tablet 250mg

1 Tablet

2.20

1487(E)

27-03-2025

28

Cloxacillin

Powder for Injection250mg

Each Pack

5.67

1487(E)

27-03-2025

29

Coagulation factor IX

Powder for Injection 600 IU

Each Pack

15708.08

1487(E)

27-03-2025

30

Coagulation factor VIII

Powder for Injection 250 IU

Each pack

4761.81

1487(E)

27-03-2025

31

Coagulation factor VIII

Powder for Injection 500 IU

Each Pack

11685.13

1487(E)

27-03-2025

32

Cyclosporine

Injection 50

mg/ml

1 ml

343.86

1487(E)

27-03-2025

33

Daunarubicin

Powder for I.V. Injection 20 mg

(5 mg/ml)

Each pack

310.03

1487(E)

27-03-2025

34

Dextran-40

Injection 10%

1 ml

1.08

1487(E)

27-03-2025

35

Diazepam

Oral Liquid 2 mg/5ml

1 ml

3.48

1487(E)

27-03-2025

36

Diclofenac

Capsule 50 mg

1 Capsule

0.78

1487(E)

27-03-2025

37

Dicyclomine

Oral Solution 10mg/5ml

1 ml

0.20

1487(E)

27-03-2025

38

Dicyclomine

Tablet 10mg

1 Tablet

0.13

1487(E)

27-03-2025

39

Dinoprostone

Tablet 0.5mg

1 Tablet

63.80

1487(E)

27-03-2025

40

Diphtheria antitoxin

10000 IU

Each Pack

1670.88

1487(E)

27-03-2025

41

DPT vaccine

Per 0.5 ml

18.07

1487(E)

27-03-2025

42

Ferrous Salt (A) + Folic Acid (B)

Tablet 100mg elemental iron (A)

+ 500mcg (B)

1 Tablet

0.28

1487(E)

27-03-2025

43

Fluconazole

Oral Liquid 50mg/5ml

1 ml

3.33

1487(E)

27-03-2025

44

Gadobenate

Injection 529

mg/ml

1 ml

138.95

1487(E)

27-03-2025

45

Glucose

Injection 50%

1 ml

0.62

1487(E)

27-03-2025

46

Glucose

Injection 5%

1000ml Glass

81.87

1487(E)

27-03-2025

47

Glucose

Injection 5%

1000ml Non- Glass

66.10

1487(E)

27-03-2025

48

Glucose

Injection 5%

100ml Glass

22.99

1487(E)

27-03-2025

49

Glucose

Injection 5%

100ml Non- Glass

20.80

1487(E)

27-03-2025

50

Glucose

Injection 5%

250ml Glass

31.75

1487(E)

27-03-2025

51

Glucose

Injection 5%

250ml Non- Glass

28.70

1487(E)

27-03-2025

52

Glucose

Injection 5%

500ml Glass

45.08

1487(E)

27-03-2025

53

Glucose

Injection 5%

500ml Non- Glass

38.89

1487(E)

27-03-2025

54

Glucose

Injection 10%

Each Pack (1000 ml)

32.93

1487(E)

27-03-2025

55

Glucose

Injection 10%

Each Pack (500 ml)

35.81

1487(E)

27-03-2025

56

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

1000ml Glass

82.41

1487(E)

27-03-2025

57

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

1000ml Non- Glass

66.59

1487(E)

27-03-2025

58

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

100ml Glass

23.04

1487(E)

27-03-2025

59

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

100ml Non- Glass

20.82

1487(E)

27-03-2025

60

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

250ml Glass

31.89

1487(E)

27-03-2025

61

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

250ml Non- Glass

28.80

1487(E)

27-03-2025

62

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

500ml Glass

45.29

1487(E)

27-03-2025

63

Glucose (A) + Sodium Chloride (B)

Injection 5% (A)

+ 0.9% (B)

500ml Non- Glass

39.12

1487(E)

27-03-2025

64

Glutaraldehyde

Solution 2%

1 ml

0.08

1487(E)

27-03-2025

65

Griseofulvin

Tablet 125mg

1 Tablet

1.05

1487(E)

27-03-2025

66

Griseofulvin

Tablet 375 mg

1 Tablet

5.48

1487(E)

27-03-2025

67

Haemodialysis fluid

As license

1 ml

0.04

1487(E)

27-03-2025

68

Hydrochlorothiazide

Tablet 50 mg

1 Tablet

0.10

1487(E)

27-03-2025

69

Hydrogen peroxide

Solution 6%

1 ml

0.04

1487(E)

27-03-2025

70

Hydroxocobalamin

Injection 1 mg/ml

1 ml

12.60

1487(E)

27-03-2025

71

Ibuprofen

Capsule 200 mg

1 Soft gelatin capsule

3.41

1487(E)

27-03-2025

72

Imatinib

Capsule 400 mg

1 Capsule

325.64

1487(E)

27-03-2025

73

Ipratropium

Inhalation (MDI/DPI) 20

mcg/dose

1 Dose

0.78

1487(E)

27-03-2025

74

Ketamine

Injection 10

mg/ml

1 ml

13.51

1487(E)

27-03-2025

75

Levonorgestrel

Tablet 0.75 mg

1 Tablet

29.34

1487(E)

27-03-2025

76

Levothyroxine

Tablet 37.50 mcg

1 Tablet

1.51

1487(E)

27-03-2025

77

Lignocaine (A) + Adrenaline (B)

Injection 1% (A)

+ 1:200000 (5

mcg/ml) (B)

1 ml

0.57

1487(E)

27-03-2025

78

Lopinavir (A) + Ritonavir (B)

Tablet 100 mg(A)

+ 25 mg(B)

1 Tablet

29.98

1487(E)

27-03-2025

79

Methotrexate

Injection 50

mg/ml

1 ml

51.06

1487(E)

27-03-2025

80

Methylrosanilinium chloride (Gentian Violet)

Paint 1%

1 ml

0.10

1487(E)

27-03-2025

81

Methylthioninium chloride (Methylene blue)

Injection 10mg/ml

1 ML

27.78

1487(E)

27-03-2025

82

Midazolam

Tablet 7.5mg

1 Tablet

28.61

1487(E)

27-03-2025

83

Morphine

SR Tablet 30 mg

1 Tablet

6.94

1487(E)

27-03-2025

84

Morphine

Tablet 10 mg

1 Tablet

6.79

1487(E)

27-03-2025

85

N-acetylcysteine

Sachet 200mg

1 gm

11.46

1487(E)

27-03-2025

86

Nevirapine

Oral Liquid 50 mg/5ml

1 ml

1.07

1487(E)

27-03-2025

87

Omeprazole

Tablet 10 mg

1 Tablet

5.66

1487(E)

27-03-2025

88

Oral poliomyelitis vaccine

1 ml

130.73

1487(E)

27-03-2025

89

Para-aminosalicylic acid

Granules (As licensed)

1 gm

3.62

1487(E)

27-03-2025

90

Paracetamol

Injection 150

mg/ml

Each Pack ( 0.5 ml)

3.92

1487(E)

27-03-2025

91

Paracetamol

Injection 150

mg/ml

Each Pack (1 ml)

5.34

1487(E)

27-03-2025

92

Paracetamol

Injection 150

mg/ml

Each Pack (3 ml)

11.10

1487(E)

27-03-2025

93

Paracetamol

Injection 150

mg/ml

Each Pack (4 ml)

13.98

1487(E)

27-03-2025

94

Paracetamol

Injection 150

mg/ml

Each Pack (5 ml)

16.86

1487(E)

27-03-2025

95

Paracetamol

Injection 150

mg/ml

Each Pack (7 ml)

22.60

1487(E)

27-03-2025

96

Penicillamine

Capsule 250 mg

1 Capsule

18.94

1487(E)

27-03-2025

97

Phenylephrine

Drop 10%

1 ml

10.31

1487(E)

27-03-2025

98

Phenylephrine

Drops 5%

1 ml

4.75

1487(E)

27-03-2025

99

Phenytoin

ER Capsule 300 mg

1 Capsule

4.85

1487(E)

27-03-2025

100

Phenytoin

Injection 25

mg/ml

1 ml

3.20

1487(E)

27-03-2025

101

Pilocarpine

Drops 4%

1 ml

14.89

1487(E)

27-03-2025

102

Potassium permanganate

Crystals for topical solution

1 gm

0.56

1487(E)

27-03-2025

103

Povidone iodine

Scrub 7.5%

1 ml

2.04

1487(E)

27-03-2025

104

Praziquantel

Tablet 600 mg

1 Tablet

44.29

1487(E)

27-03-2025

105

Prednisolone

Injection 20

mg/2ml

1 ml

4.57

1487(E)

27-03-2025

106

Pyrazinamide

Oral Liquid 250 mg/5ml

1 ml

0.78

1487(E)

27-03-2025

107

Rifampicin

Tablet 150 mg

1 Tablet

2.05

1487(E)

27-03-2025

108

Ringer Lactate

Injection 1000ml

Each Pack

101.71

1487(E)

27-03-2025

109

Ringer Lactate

Injection 100ml

Each Pack

26.62

1487(E)

27-03-2025

110

Ringer Lactate

Injection 250ml

Each Pack

45.39

1487(E)

27-03-2025

111

Ringer Lactate

Injection 500ml

Each Pack

57.85

1487(E)

27-03-2025

112

Ritonavir

Capsule 100 mg

1 Capsule

35.98

1487(E)

27-03-2025

113

Salbutamol

Capsule 4 mg

1 Capsule

0.75

1487(E)

27-03-2025

114

Silver Sulphadiazine

Cream 1%

1 gm

0.64

1487(E)

27-03-2025

115

Sodium Chloride

Injection 0.9%

1000ml Glass

75.66

1487(E)

27-03-2025

116

Sodium Chloride

Injection 0.9%

1000ml Non- Glass

59.67

1487(E)

27-03-2025

117

Sodium Chloride

Injection 0.9%

100ml Glass

22.36

1487(E)

27-03-2025

118

Sodium Chloride

Injection 0.9%

100ml Non- Glass

20.15

1487(E)

27-03-2025

119

Sodium Chloride

Injection 0.9%

250ml Glass

30.17

1487(E)

27-03-2025

120

Sodium Chloride

Injection 0.9%

250ml Non- Glass

27.08

1487(E)

27-03-2025

121

Sodium Chloride

Injection 0.9%

500ml Glass

41.95

1487(E)

27-03-2025

122

Sodium Chloride

Injection 0.9%

500ml Non- Glass

35.71

1487(E)

27-03-2025

123

Sodium nitrite

Injection 30

mg/ml

1 ml

33.12

1487(E)

27-03-2025

124

Streptokinase

Injection 7,50,000 IU

Each Pack

1605.06

1487(E)

27-03-2025

125

TD Vaccine

Each dose of 0.5ml contains: Diphtheria Toxoid

≤5Lf (≥ 2IU) Tetanus Toxoid ≥ 5Lf (≥ 40IU)

Each 0.5ml Pack

23.89

1487(E)

27-03-2025

126

TD Vaccine

Each dose of 0.5ml contains: Diphtheria Toxoid

≤5Lf (≥ 2IU) Tetanus Toxoid ≥ 5Lf (≥ 40IU)

Each 5ml Pack

224.52

1487(E)

27-03-2025

127

TD Vaccine

Each dose of 0.5ml contains: Diphtheria Toxoid

≤25Lf (≥ 30IU)

Tetanus Toxoid ≥ 5Lf (≥ 40IU)

Each 0.5ml Pack

20.48

1487(E)

27-03-2025

128

Temozolomide

Tablet 100 mg

1 Tablet

1971.83

1487(E)

27-03-2025

129

Timolol

Drops 0.25%

1 ml

6.59

1487(E)

27-03-2025

130

Tramadol

Injection 50

mg/ml (20 ml Pack)

1 ml

1.59

1487(E)

27-03-2025

131

Verapamil

Injection 2.5

mg/ml

1 ml

1.50

1487(E)

27-03-2025

132

Vinblastine

Injection 1mg/ml

1 ml

26.15

1487(E)

27-03-2025

133

Vitamin A

Capsule 50000 IU

1 Capsule

0.69

1487(E)

27-03-2025

134

Water for Injection

Injection

Each Pack (5 ml)

2.86

1487(E)

27-03-2025

135

Water for Injection

Injection

Per 500 ml Pack

58.78

1487(E)

27-03-2025

136

Water for Injection

Injection

Per 1000 ml Pack

103.16

1487(E)

27-03-2025

137

Zidovudine

Capsule 300 mg

1 Capsule

2.63

1487(E)

27-03-2025

138

Zolpidem

Capsule 5 mg

1 Capsule

9.37

1487(E)

27-03-2025

Furthermore, the notification further added:

(a) The ceiling prices are applicable with effect from 1.4.2026 (ceiling prices are inclusive of Wholesale Price Index (WPI) @ 0.64956% for the year 2025 over 2024).

(b) In respect of formulation where pack wise ceiling price is notified, for any other pack size manufactured, the manufacturer shall approach NPPA under para 11(3) of DPCO, 2013 for specific price approval for its formulations.

(c) In respect of any other scheduled formulation, for which ceiling price is not mentioned above, the manufacturer shall approach NPPA for specific price approval for its formulations.

(d) All manufacturers of scheduled formulations, selling the branded or generic or both the versions of scheduled formulations at a price higher than the ceiling price (plus Goods and Services Taxes as applicable) so fixed and notified by the Government, shall revise the prices of all such formulations downward not exceeding the ceiling price specified in column (5) in the above table plus Goods and Services Taxes as applicable, if any.

(e) All the existing manufacturers of above-mentioned scheduled formulations having MRP lower than the ceiling price notified vide S.O. No. & date as specified in column 6 (a)& 6 (b) in the above table (plus Goods and Services Taxes as applicable, if any), may revise the existing M.R.P. of their formulations, on the basis of WPI @ 0.64956% for year 2025 over 2024 in accordance with paragraph 16(2) of DPCO, 2013.

(f) The manufacturers may add Goods and Services Taxes only if they have paid actually or if it is payable to the Government on the ceiling price mentioned in column (5) of the above said table.

(g) Information about the revision, if carried out, shall be forwarded to the Government in either electronic or physical form in Form-II within a period of fifteen days of such revision and non-submission of information under this sub-paragraph shall be construed as non-revision of maximum retail price (MRP) and the concerned manufacturer shall be liable to deposit the amount charged over and above the pre-revised maximum retail price (MRP), along with interest thereon from the date of overcharging.

(h) The ceiling price for a pack of the scheduled formulation shall be arrived at by the concerned manufacturer in accordance with the ceiling price specified in column (5) of the above table as per provisions contained in paragraph 11 of the DPCO, 2013. The manufacturer shall issue a price list in Form–V from date of Notification as per paragraph 24 of the DPCO, 2013 to NPPA through IPDMS and submit a copy to State Drug Controller and dealers.

(i) As per para 24(4) of DPCO 2013, every retailer and dealer shall display price list and the supplementary price list, if any, as furnished by the manufacturer, on a conspicuous part of the premises where he carries on business in a manner so as to be easily accessible to any person wishing to consult the same.

(j) Where an existing manufacturer of scheduled formulation with dosage or strength or both as specified in the above table launches a new drug as per paragraph 2 (1) (u) of the DPCO, 2013 such existing manufacturer shall apply for prior price approval of such new drug to the NPPA in Form-I as specified under Schedule-II of the DPCO, 2013.

(k) The manufacturers of above said scheduled formulations shall furnish quarterly return to the NPPA, in respect of production / import and sale of scheduled formulations in Form-III of Schedule-II of the DPCO, 2013 through IPDMS. Any manufacturer intending to discontinue production of above said scheduled formulation shall furnish information to the NPPA, in respect of discontinuation of production and / or import of scheduled formulation in Form-IV of Schedule-II of the DPCO, 2013 at least six months prior to the intended date of discontinuation.

(l) The manufacturers not complying with the ceiling price and notes specified hereinabove shall be liable to deposit the overcharged amount along with interest thereon under the provisions of the DPCO, 2013 read with Essential Commodities Act, 1955.

(m) Consequent to the issue of ceiling prices of such formulations as specified in column (2) of the above table in this notification, the price order(s) fixing ceiling or retail price, if any, issued prior to the above said date of notification, stand(s) superseded.

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