NPPA Revises Prices of Piperacillin-Tazobactam Injections, Sets Ceiling at Rs 470 per Bag
New Delhi: Through a recent notification, the National Pharmaceutical Pricing Authority (NPPA), Ministry of Chemicals and Fertilizers, Government of India, has revised the ceiling prices of Piperacillin plus Tazobactam injections in dual chamber bags based on the annual Wholesale Price Index (WPI) for 2025.
The price revision reflects a marginal increase of 0.64956% over the previous year (2024), and will come into effect from April 1, 2026.
The revised ceiling prices apply to Piperacillin + Tazobactam injections in dual chamber bags with special features.
As per the notification, the ceiling price for Piperacillin 2 g + Tazobactam 250 mg injection has been fixed at Rs. 225.56 per dual chamber bag, while Piperacillin 4 g + Tazobactam 500 mg injection has been revised to Rs. 470.34 per dual chamber bag.
The formulations covered under this notification include products manufactured by M/s Gufic Biosciences Limited under the brand name Tazofic Injection (DCB).
In exercise of powers, conferred by sub paragraph (3) and (4) of paragraph 11, 14 and 16 of the Drugs (Prices Control) Order, 2013, read with S.O. 1394(E) dated 30th May, 2013, S.O. 1192(E) dated 22nd March, 2016 and S.O. 5249(E) dated 11th November, 2022 issued by the Government of India in the Ministry of Chemicals and Fertilizers and in supersession of the order of the Government of India in the Ministry of Chemicals and Fertilizers (National Pharmaceutical Pricing Authority) S.O. No. 1475(E) dated 27.03.2025 in so far as it relate to formulation packs mentioned in the Table A below, manufactured by the manufacturers specified in Table B for specified products and pack-sizes, except in respect of things done or omitted to be done before such supersession, the National Pharmaceutical Pricing Authority, has revised the price based on Wholesale price index (WPI) of 2025 as specified in column (5) of the Table A herein below as separate ceiling price exclusive of Goods and Services Tax applicable, if any, in respect of the scheduled formulations specified in the corresponding entry in column (2) of the said Table with the dosage form and strength and unit/packaging specified respectively in the corresponding entries in columns (3) and (4) thereof:
Table A: Price Revision as per Annual Wholesale Price Index (WPI) @ 0.64956% increase
| Sl. No. | Medicines | Dosage form and Strength | Unit | Ceiling price (w.e.f. 1.4.2026 with WPI @ 0.64956%) (in Rs.) |
|---|---|---|---|---|
| 1 | Piperacillin (A) + Tazobactam (B) | Powder for Injection 2 g (A) + 250 mg (B) | Per Dual chamber bag with special feature | 225.56 |
| 2 | Piperacillin (A) + Tazobactam (B) | Powder for Injection 4 g (A) + 500 mg (B) | Per Dual chamber bag with special feature | 470.34 |
Table B
| Sl. No. | Name of Manufacturer | Product / Brand Name |
|---|---|---|
| 1 | M/s Gufic Biosciences Limited | Tazofic Injection (DCB) |
The notification further clarified
(a) The ceiling prices are applicable with effect from 1.4.2026 (ceiling prices are inclusive of Wholesale Price Index (WPI) @ 0.64956% for the year 2025 over 2024).
(b) The manufacturers of scheduled formulations, selling above said products/brands of scheduled formulations at price higher than the ceiling price (plus Goods and Services Tax as applicable) so fixed and notified by the Government, shall revise the prices of all such formulations downward not exceeding the ceiling price specified in column (5) in the above Table A plus Goods and Services Tax as applicable, if any.
(c) The manufacturers of above-mentioned scheduled formulations having MRP lower than the ceiling price notified vide S.O. No. 1475(E) dated 27.03.2025 (plus Goods and Services Tax as applicable, if any), may revise the existing M.R.P. of their formulations, on the basis of WPI @ 0.64956% for year 2025 over 2024 in accordance with paragraph 16(2) of DPCO, 2013.
(d) The manufacturers may add Goods and Services Tax only if they have paid actually or if it is payable to the Government on the ceiling price mentioned in column (5) of the above said Table A.
(e) Any other manufacturer claiming separate ceiling price for Piperacillin (A) + Tazobactam (B) Injection (i) Powder for injection 2g (A) + 250mg (B) (ii) 4g (A) + 500mg (B) Per Dual chamber bag having special features shall apply to NPPA for separate ceiling price approval.
(f) Information about the revision, if carried out, shall be forwarded to the Government in either electronic or physical form in Form-II within a period of fifteen days of such revision and non-submission of information under this subparagraph shall be construed as non-revision of maximum retail price (MRP) and the concerned manufacturer shall be liable to deposit the amount charged over and above the pre-revised maximum retail price (MRP), along with interest thereon from the date of overcharging.
(g) The ceiling price for a pack of the scheduled formulation shall be arrived at by the concerned manufacturer in accordance with the ceiling price specified in column (5) of the above Table A as per provisions contained in paragraph 11 of the Drugs (Prices Control) Order, 2013. The manufacturer shall issue a price list in Form–V from date of Notification as per paragraph 24 of the DPCO, 2013 to NPPA through IPDMS and submit a copy to State Drug Controller and dealers.
(h) As per para 24(4) of DPCO 2013, every retailer and dealer shall display price list and the supplementary price list, if any, as furnished by the manufacturer, on a conspicuous part of the premises where he carries on business in a manner so as to be easily accessible to any person wishing to consult the same.
(i) Where an existing manufacturer of scheduled formulation with dosage or strength or both as specified in the above Table A launches a new drug as per paragraph 2 (1) (u) of the DPCO, 2013 such existing manufacturer shall apply for prior price approval of such new drug to the NPPA in Form I as specified under Schedule-II of the DPCO, 2013.
(j) The manufacturers of above said scheduled formulations shall furnish quarterly return to the NPPA, in respect of production / import and sale of scheduled formulations in Form-III of Schedule-II of the DPCO, 2013 through IPDMS. Any manufacturer intending to discontinue production of above said scheduled formulation shall furnish information to the NPPA, in respect of discontinuation of production and / or import of scheduled formulation in Form-IV of Schedule-II of the DPCO, 2013 at least six months prior to the intended date of discontinuation.
(k) The manufacturers not complying with the ceiling price and notes specified hereinabove shall be liable to deposit the overcharged amount along with interest thereon under the provisions of the Drugs (Prices Control) Order, 2013 read with Essential Commodities Act, 1955. (l) Consequent to the issue of ceiling prices of such formulations as specified in column (2) of the above Table A in this notification, the price order(s) fixing ceiling or retail price, if any, issued prior to the above said date of notification, stand(s) superseded.
To view the official notice, click the link below:
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