Sanofi Pasteur, Translate Bio begin Phase 1/2 clinical trial of mRNA COVID-19 vaccine
Paris and Lexington: Sanofi Pasteur, the vaccines global business unit of Sanofi, and Translate Bio, a clinical-stage messenger RNA (mRNA) therapeutics company, have recently announced the start of the Phase 1/2 clinical trial for MRT5500, an mRNA vaccine candidate against SARS-CoV-2, the virus that causes COVID-19. The Companies expect interim results from this trial in the third quarter of 2021.
"Our mRNA vaccine candidate is the result of our expertise in infectious diseases coupled with the innovative technologies of our partner," said Thomas Triomphe, Executive Vice President and Global Head of Sanofi Pasteur. "Initiating the Phase 1/2 trial represents an important step forward in our goal of bringing another effective vaccine to the ongoing fight against the COVID-19 pandemic."
"We have made important progress towards developing mRNA vaccine candidates for infectious diseases through our collaboration with our partner Sanofi Pasteur," said Ronald Renaud, Chief Executive Officer of Translate Bio. "With the impact of mRNA vaccines demonstrated during the pandemic, our joint development team remains steadfast in our commitment to advancing MRT5500 as part of the collaborative effort to overcome this global health crisis."
Clinical trial participants will receive one dose of MRT5500, or two doses 21 days apart. Three different dose levels will be investigated (15µg, 45µg or 135µg).
Read also: Sanofi, GSK begin Phase 2 study of protein-based COVID-19 vaccine
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