Sentynl Therapeutics, a Zydus company acquires Zokinvy for Progeria from Eiger Biopharma
Ahmedabad: Sentynl Therapeutics, Inc., a U.S.-based biopharmaceutical company wholly-owned by Zydus Lifesciences Ltd. (Zydus Group), and Eiger BioPharmaceuticals, Inc., a commercial-stage biopharmaceutical company focused on the development of innovative therapies for rare metabolic diseases, have announced the closing of the sale of Eiger’s Zokinvy (lonafarnib) program to Sentynl.
Zokinvy is the treatment approved by the U.S. Food and Drug Administration (FDA) to target the cause and symptoms of Progeria, also known as Hutchinson-Gilford Progeria Syndrome (HGPS), and Processing-Deficient Progeroid Laminopathies (PDPL) in young people 12 months of age and older. Collectively known as Progeria, HGPS and PDPL are ultra-rare, fatal, genetic premature aging diseases that accelerate mortality in young patients.
Following its U.S. approval in 2020, Zokinvy secured approval in the European Union and Great Britain (2022) and in Japan (January 2024).
Speaking on the acquisition, Dr. Sharvil Patel, Managing Director of Zydus Lifesciences Ltd, said, “This acquisition marks an important milestone in growing our portfolio of medicines for rare and orphan diseases, which can have devastating consequences if left untreated. We are focused on supporting patients to live healthier and more fulfilled lives. The acquisition of Zokinvy furthers this mission, as it has demonstrated a meaningful impact on young patients and their families.” “It is an honor to add Zokinvy to our portfolio of products that have a tangible impact on the lives of rare disease patients, whose needs are too often unmet or overlooked,” said Matt Heck, President & Chief Executive Officer of Sentynl. “We are firmly committed to provide best-in-class global access to Zokinvy and are eager to serve the patients and their families affected by Progeria. We are grateful to Eiger and The Progeria Research Foundation for their dedicated effort to develop and secure availability of this lifechanging product.”
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