SII partners with Univercells to bring affordable personalized oncology to masses

At present, personalised care options such as novel cancer vaccines and specialised immunotherapies are accessible to a few patients only. These new therapies are developed using genetic material extracted from the patient’s tumours, a process which is both time-consuming, and expensive. Besides, due to strict regulatory limitations on the sequence, transfer, and manufacturing of genetic material, these treatments are only available in a handful of countries. This collaboration between SII and Univercells will help in addressing these challenges, with a view to capture a proportion of the global cancer care market.

“We are excited about this collaboration with Univercells with an aim to strengthen the accessibility of cancer care therapies, which may prove to be a boon for cancer treatment across the world, especially in the LMIC’s,” said Dr. Umesh Shaligram, Executive Director, R&D, SII. He further added, “Relapse rates for many cancers are very high, especially for patients who are diagnosed at a later stage. To address this, we are developing unique point-of-care cancer treatment using mRNA in combination with our Recombinant BCG (VPM1002).”

“Our technology can cut months off the time to create a personalised therapeutic without compromising quality.” said José Castillo, Chief Technology Officer & co-founder of Univercells. “We’ve completely redesigned the manufacturing process from first principles and believe that we can save up to 90% of costs of producing these medicines compared to traditional approaches.”

Critically, Univercells’ technology also supports very-small scale, local production. This allows countries, and even hospitals, to provide personalised therapies produced locally. With SII’s global reach, these therapies can reach patients in Europe, India and the African continent.

"Longer term, Univercells and SII believe that they may be able to dramatically accelerate the progress of new medicines," the release stated.

At present, the average time for a cancer therapy to go from patenting to use by patients is close to 15 years in the UK.

“Our target is to reduce that delay to just 3 years.” said José Castillo. “We have many barriers to overcome, but because we can automate the system, we believe we can produce personalised therapeutics which still meet the highest standards of quality and are acceptable to the regulators. There are breakthroughs all the time, but too many are coming too late for the patients who need them. This partnership will help us change that.”

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