USFDA inspection: Piramal Pharma gets Form 483 with 6 observations for Lexington facility

The observations were classified under VAI (Voluntary Action Indicated) and does not relate to data integrity.

Published On 2023-01-12 06:02 GMT   |   Update On 2023-04-04 06:29 GMT
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Mumbai: Piramal Pharma has recently announced that the US Food and Drug Administration (USFDA) has issued a Form-483, with six observations at the conclusion of the inspection at the company's facility located at Lexington (Kentucky, USA).

 An FDA Form 483 is issued to firm management at the conclusion of an inspection when an investigator(s) has observed any conditions that in their judgment may constitute violations of the Food Drug and Cosmetic (FD&C) Act and related Acts.

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USFDA conducted a Pre-Approval Inspection (PAI) and Good Manufacturing Practices (GMP) inspection of Piramal Pharma Limited's Lexington facility from 27th December 2022 to 10th January, 2023.

The observations were classified under VAI (Voluntary Action Indicated) and does not relate to data integrity.

"The Company is preparing a detailed response to the observations, which will be submitted to the US FDA within the stipulated timelines," Piramal stated in a BSE filing.

 "The Company remains committed to maintain the highest standards of compliance and will work closely with the agency to comprehensively address all the observations," Piramal Pharma further stated.

Read also: Gland Pharma gets UFSDA EIR for Dundigal Facility

Piramal Pharma Limited offers a portfolio of differentiated products and services through end-to-end manufacturing capabilities across 15 global facilities and a global distribution network in over 100 countries. PPL includes Piramal Pharma Solutions (PPS), an integrated Contract Development and Manufacturing Organization; Piramal Critical Care (PCC), a Complex Hospital Generics business, and the India Consumer Healthcare business selling over-the-counter products. PPS offers end-to-end development and manufacturing solutions through a globally integrated network of facilities across the drug life cycle to innovators and generic companies. PCC’s complex hospital product portfolio includes inhalation anaesthetics, intrathecal therapies for spasticity and pain management, injectable pain and anaesthetics, injectable anti-infectives, and other therapies.
In addition, PPL has a joint venture with Allergan. In October 2020, the company received a growth equity investment from the Carlyle Group.

Read also: Piramal Pharma gets SEBI nod to list shares on Indian stock exchanges

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