Adipokines: A New Tool for Early Detection of Metabolic Syndrome in PCOS patients, Study Finds
India: A recent study published in Cureus has found that over 40.2% of women with polycystic ovary syndrome (PCOS) developed metabolic syndrome (MetS) and identified a strong link between altered adipokine levels and the early stages of MetS development.
"Adipokines such as adiponectin, leptin, and resistin showed significant variations between women with and without MetS, suggesting their potential as early biomarkers for detection and intervention," the researchers reported. "In contrast, traditional indicators like fasting glucose, waist circumference, and triglyceride levels were more predictive in later stages, reinforcing the value of adipokines in the early diagnosis and management of MetS in PCOS patients."
Women with polycystic ovary syndrome are more likely to develop metabolic syndrome, as both conditions share common underlying factors. Adipokines—hormones produced by fat tissue—play a key role in this link by affecting how fat is stored and used in the body. These changes in fat metabolism can contribute to the development of MetS.
To better understand this connection, Chaitali Maitra, Biochemistry, Dr. S.S. Tantia Medical College Hospital and Research Centre, Sri Ganganagar, IND, and colleagues looked at adipokine levels in women with PCOS, both with and without MetS, aiming to explore whether these molecules could serve as early warning signs for metabolic complications in PCOS patients.
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