Antenatal corticosteroid use reduces respiratory morbidity in babies born in the late preterm period: Study
Nigeria: The administration of antenatal corticosteroids (ACS) has long been considered a cornerstone in preterm labor management, aimed at improving neonatal outcomes, particularly respiratory health. However, a recent study published in BMC Pregnancy and Childbirth delves into the efficacy of ACS, specifically in babies born during the late preterm period, shedding light on its impact on respiratory morbidity.
The study found that dexamethasone administration to women at risk for late preterm delivery significantly reduces the rate of neonatal intensive care unit admission, neonatal respiratory complications, and the need for active resuscitation at birth.
Most studies have used dexamethasone or betamethasone as the antenatal steroid. Current research has not shown any significant differences in complication or efficacy of both drugs, hence the choice of dexamethasone in this study. Also, the study was done in a low-resource setting where dexamethasone is significantly cheaper than betamethasone. Considering this, Khadijah A. Shittu, Department of Obstetrics & Gynaecology, Lagos State University Teaching Hospital, Lagos, Nigeria, and colleagues aimed to determine whether antenatal corticosteroids use reduces respiratory morbidity in late preterm babies in the Nigerian population.
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