Asthma linked to recurrent pregnancy loss, finds study
Asthma is linked to recurrent pregnancy loss according to a recent study published in The Journal of Allergy and Clinical Immunology: In Practice
Women with asthma appear to have an increased risk of pregnancy loss. The impact of asthma on recurrent pregnancy loss (RPL), defined as three consecutive losses, is, however, unknown.
The aim of this study was to investigate if having asthma before or during the fertile age is associated with pregnancy loss and RPL.
Based on Danish national health registers, we identified all women aged 6 to 45 years with at least two filled prescriptions of an anti-asthma drug during the period 1977 to 2019. Women with asthma were compared to women without asthma. Pregnancy outcomes were retrieved for both groups from national health registers. Logistic regression with adjustment for year of birth and educational level provided odds ratios (OR) for a number of pregnancy losses. Subgroup analyses were conducted for early-onset (age 6-15), adult-onset (age 16-39) and late-onset (age 40-45) asthma. Lastly, they compared uncontrolled asthma (defined as ≥ 400 doses of Short-acting β2-agonist in a year) to controlled asthma (defined as < 400 doses of short-acting b2-agonist in a year).
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