Black Cohosh Safe but Lacks Evidence on improving pregnancy in PCOS: Study
Polycystic ovary syndrome (PCOS) is a complex, common reproductive and endocrine disorder affecting up to 17.8% of reproductive-aged women. In a recent study, researchers have reported that black cohosh is safe but lack high-quality evidence supporting the effectiveness in PCOS. The study findings were published in the Journal of Pharmacy Practice on April 29, 2021.
Black cohosh, also known as black bugbane and black snakeroot, among other names, has been a popular medicinal herb in North America for centuries, and it is still valued to this day. Black cohosh modern applications are focused on treating the symptoms of menopause and menstrual complaints. It also occasionally used in the management of PCOS-related infertility. To further evaluate its action, Dr Chi Wai Fan and his team conducted a study in which they assessed the safety and efficacy of black cohosh for ovulation-induction through hormone regulation and increased endometrial thickness to improve pregnancy rates in women with PCOS-related infertility.
In this systemic review, researchers searched Medline, Embase, International Pharmaceutical Abstracts, Science Direct, and Cumulative Index of Nursing and Allied Health Literature spanning origin to December 19, 2020. They also searched the National Clinical Trials database and the International Clinical Trials Registry Platform for additional records. They screened 181 records and included 2 randomized controlled trials (RCT). They also identified 4 additional records (3 published) for the analysis.
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