Can Use of flurbiprofen ester in 4-dimensional hysterosalpingography relieve pain during an infertility evaluation?

Tubal patency reduced pain during ultrasound tubal examination, flurbiprofenate provided significant analgesia after ultrasound tubalography and reduced adverse effects (P < 0.001). The tube diameter thickness had no effect on tubal ultrasonography procedure-related pain. Multivariable analysis of pain relief during imaging suggested that the use of flurbiprofen for bilateral tubal patency had a significant positive effect on pain relief within 30 min after the examination with an AUC of 0.732 (95% CI: 0.665–0.798).

A flurbiprofen ester continuous intravenous drip had a good analgesic effect in patients with TVS 4D-HyCoSy. Specifically, the pain relief effect after examination was significant and reduced the incidence of adverse reactions during the contrast examination. Flurbiprofen ester can be administered independently and is worthy of clinical promotion and application.

Reference:

Long Tan, Shiji Wu and Ailin Ma et al. Use of Flurbiprofen Ester in 4-Dimensional Hysterosalpingography: Does Flurbiprofen Ester Relieve Pain During an Infertility Evaluation?. BIOI. 2024. Vol. 5(1). DOI: 10.15212/bioi-2024-0026.