Early Medication Abortion Noninferior to Standard Treatment: New Randomized Trial Finds
Sweden: A new randomized trial investigating the effectiveness of very early medication abortion has revealed promising results, suggesting that initiating the procedure before confirmation of an intrauterine pregnancy may be just as effective as the standard, delayed treatment approach.
The study, published in the New England Journal of Medicine, revealed that initiating medication abortion before confirming an intrauterine pregnancy is noninferior to the standard delayed treatment in terms of achieving a complete abortion.
Medication abortion, which involves taking a combination of mifepristone and misoprostol, is a well-established method for terminating early pregnancies and is considered highly effective and safe. Traditionally, the treatment begins after the pregnancy is confirmed, typically around six weeks of gestation, using ultrasound or other methods to verify the presence of an intrauterine pregnancy.
Against the above background, Karin Brandell, Karolinska Institutet, Department of Women’s and Children’s Health, Division of Obstetrics and Gynecology, Stockholm, Sweden, and colleagues assessed the efficacy and safety of medication abortion at very early gestations, before the pregnancy can be visualized through ultrasonography.
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