Early periods linked to severe vasomotor symptoms at menopause: Study

Written By :  Dr. Kamal Kant Kohli
Published On 2020-07-24 04:00 GMT   |   Update On 2020-07-24 09:13 GMT

Researchers at University of Queensland have found in a new study that early menstruation increases the likelihood of hot flushes and nights sweats decades later at menopause.Early age at menarche is a risk factor for vasomotor menopausal symptoms, particularly for frequent VMS, but midlife BMI may play an important role in modifying this risk.The new research has been published in...

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Researchers at University of Queensland have found in a new study that early menstruation increases the likelihood of hot flushes and nights sweats decades later at menopause.Early age at menarche is a risk factor for vasomotor menopausal symptoms, particularly for frequent VMS, but midlife BMI may play an important role in modifying this risk.

The new research has been published in the International Journal of Obstetrics & Gynaecology.
The researchers conducted a pooled analysis of six cohort studies to
examine the association between age at menarche and risk of vasomotor menopausal symptoms (VMS) and whether midlife body mass index (BMI) modified the association.

School of Public Health researchers analysed data from more than 18,000 middle aged women across the UK, USA and Australia, as part of the Life course Approach to reproductive health and Chronic disease Events (InterLACE) international collaboration.

UQ's Dr Hsin-Fang Chung said the study showed women who started menstruating aged 11 or younger had a 50 per cent higher risk of experiencing frequent hot flushes and night sweats - known as vasomotor symptoms - at menopause.

The group was compared with women who had their first period at 14 or older.

"The risk of the women who menstruated early experiencing both symptoms was greater than having either hot flushes or night sweats alone," Dr Chung said.

She said early menstruation previously had been linked to adverse health conditions later in life, including type 2 diabetes and cardiovascular diseases.

InterLACE project leader Professor Gita Mishra said obesity played a significant role in the findings.

"Women who experienced early menstruation and were overweight or obese in midlife had a two times greater risk of frequent hot flushes and night sweats, compared with women who experienced their first period aged 14 years or older, and had normal weight," she said.

"These findings encourage women with early menstruation to engage in health promotion programs, especially weight management in adulthood," Professor Mishra said.

For further reference log on to:

http://dx.doi.org/10.1111/1471-0528.16393 

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Article Source : International Journal of Obstetrics & Gynaecology

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