High diastolic BP in women with pre-eclampsia linked to development of eclampsia: Study
Pre-eclampsia along with complications of pulmonary oedema has reported up to 50% of maternal deaths related to pre-eclampsia. Pre-eclampsia, is pregnancy-specific disease that involves development of de-novo hypertension and end organ dysfunction.
Dr Pauli Van Heerden and their team have found in a new study that When diagnosed with pre-eclampsia, women with pulmonary oedema had increased systolic blood pressures and women with eclampsia had increased diastolic blood pressures compared to pre-eclampsia controls.
The objective of the study was to evaluate whether blood pressure and change in blood pressure measurements during pregnancy were associated with eclampsia or pulmonary oedema among women with pre-eclampsia.
The researchers designed an observational study of women with eclampsia, pre-eclampsia complicated by pulmonary oedema and pre-eclampsia without end-organ complications (pre-eclampsia controls) at a large referral center in Cape Town, South Africa. Blood pressure measurements at presentation for antenatal care were compared to measurements after a diagnosis of pre-eclampsia. Mean blood pressures and changes in blood pressures were also calculated and compared between groups at different time points. A sub analysis including women who presented for antenatal care before 20 weeks of gestation was performed.
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