Hysterectomy without adnexal surgical procedure associated with increased risk of osteoporosis: JAMA

A recent study uncovered critical insights into the long-debated association between hysterectomy and osteoporosis risk, specially among women from 40 to 59 years. The findings were published in Journal of American Medical Association.

The data from Korean National Health Insurance was analyzed to overcome limitations of previous research and provide a more precise understanding of this health concern.

The research analyzed a total of 25,910 female patients from 2003 to 2011 and matched through propensity score, with half having undergone benign hysterectomy and the other half indicating no history of the procedure during regular health checkups. The participants were tracked until December 31, 2020, to make up a median follow-up period of 10.9 years.

The results were based on whether hysterectomy was performed with or without adnexal surgical procedures. The findings revealed that patients who underwent hysterectomy without adnexal surgery faced a higher risk of osteoporosis within the initial 7 years compared to those who did not have the procedure. After this period, the risks were equalized. Also, the group undergoing hysterectomy with adnexal surgical procedures showed a persistent and higher risk of osteoporosis within the first 7 years and following years.