Low interpregnancy interval and air pollution have synergistic effect on Low Birth Weight outcomes, claims study
Researchers found that short interpregnancy intervals and exposure to air pollution during pregnancy are two risk factors for low birth weight (LBW). Recently, a research study was conducted in Nantong, China, to explore the combined effects of IPI with air pollution exposure on birth weights. The investigation showed that shorter IPIs are synergistic with high levels of air pollutants, therefore implying that optimizing birth spacing and controlling air pollution will improve birth outcomes. The study was published in BMC Public Health by Lu X. and colleagues.
This was a retrospective cohort study based on birth records from Jiangsu Maternal Child Information System that focused on the live births in Nantong from January 2020 to June 2021. According to the definition, IPI was considered as time elapsed from the delivery of a previous live birth up to the date of the last menstrual period of the subsequent pregnancy. The above was estimated based on a hybrid kriging-LUR-RF model for exposure to ambient air pollutants during pregnancy, including PM2.5 and PM10, ozone (O3), nitrogen dioxide (NO2), sulfur dioxide (SO2), and carbon monoxide (CO). An innovative air pollution score was generated by summing the concentrations of five pollutants, weighted by LBW regression coefficients, excluding CO.
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