Maternal pruritus gravidarum linked to long-term dermatology-related hospitalizations in Offspring

The team of researchers conducted a population-based, retrospective cohort study of all singleton deliveries between 1991 and 2021. The location was the tertiary medical centre.

The comparison was made between the Offspring of mothers diagnosed with and without pruritus gravidarum. ICD-9 codes were used.

The results of the study are:

• 849 women out of 356,356 deliveries met the inclusion criteria and were diagnosed with pruritus gravidarum during pregnancy, constituting 0.23%.
• Compared to Offspring to mothers with pruritus gravidarum versus non-pruritus gravidarum mothers, hospitalization rates involving dermatological morbidity were higher, with values of 7.1% vs. 4.6%.
• Pruritus gravidarum was an independent risk factor for dermatological-related hospitalizations in the Offspring after controlling for gestational age, hypertensive disorders, diabetic disorders, meconium-stained amniotic fluid exposure and fertility treatments.
• The adjusted HR was 1.44.

They said, “We recorded Maternal pruritus gravidarum as an independent risk factor for long-term dermatology-related hospitalization in the Offspring up to 18 years of age.

Further reading:

Yoad Govrin-Yehudain, Tamar Wainstock, Eyal Sheiner, Amir Horev & Yuval Krieger (2023) Maternal pruritus gravidarum and its long-term effect on dermatological morbidity in the offspring, The Journal of Maternal-Fetal & Neonatal Medicine.

https://doi.org/10.1080/14767058.2023.2241103