Maternal urinary and genital tract infections during pregnancy tied to childhood leukaemia in offspring: JAMA
China: An Original Investigation of Pediatrics published in JAMA Network Open has concluded that maternal urinary and genital tract infections during pregnancy increase the risk of childhood leukaemia in offspring. Researchers from Guangzhou Medical University reported this finding.
Maternal infection may cause chromosomal alterations in the fetus, increasing the risk of childhood leukaemia. A recent analysis shows an association between maternal influenza, rubella, and varicella during pregnancy and a higher risk of childhood leukaemia.
Maternal infection during pregnancy potentially causes fetal genetic and immunological abnormalities. This has been associated with childhood leukaemia in small cohort studies.
The question is, “In Denmark, Is there any risk association between maternal infection during pregnancy and risk of childhood leukaemia among offspring?”
Considering this background, researchers investigated the question above in 2 million Danish children. The primary outcome was acute lymphoid leukaemia (ALL) and acute myeloid leukaemia (AML).
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.