Pre-Conception Vitamin D Deficiency Increases Risk of Pregnancy Hypertension, claims research

Pre-conception vitamin D deficiency is associated with increased risk for hypertensive disorders in pregnancies in women who conceive via fresh embryo transfer and in vitro fertilization (IVF), as reported by a recent study published in Reproductive Biology and Endocrinology. The study was conducted by Aaron Chen and colleagues in China.
A total of 306 women who received IVF with fresh autologous embryo transfer participated in the retrospective cohort study, and the occurrence of adverse pregnancy outcomes, including hypertensive disorders, was compared according to vitamin D status. This study utilized archived serum samples to measure pre-conception 25-hydroxyvitamin D levels in women undergoing IVF with fresh autologous embryo transfer. The women were categorized into two groups according to their vitamin D status as follows:
• Vitamin D deficient: <20 ng/ml
• Non-deficient: ≥20 ng/ml
Pregnancy outcomes that were adverse included hypertensive disorders like gestational hypertension and pre-eclampsia as well as other complications. Adjusted odds ratios (ORs) were determined to assess the relationship between vitamin D status and pregnancy outcomes.
The results of the study were as follows:
• Of 306 women, 16 developed hypertensive disorders during pregnancy: gestational hypertension and pre-eclampsia (5.3%).
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