Preeclampsia Increase Risk of Venous Thromboembolism in Pregnancy: JAMA
In a recent observational cohort study published in Journal of American Medical Association, Eva Havers-Borgersen and team found a concerning association between preeclampsia and an increased risk of venous thromboembolism (VTE), a leading cause of maternal mortality.
The study encompassed 522,545 primiparous women who gave birth in Denmark between 1997 and 2016, revealed that 4.5% of these women were diagnosed with preeclampsia, a pregnancy-induced hypertensive disorder. The researchers observed that women with preeclampsia, though similar in age to those without the condition, exhibited a higher burden of comorbidities.
With a median follow-up period of 10.2 years, preeclampsia was found to be associated with a significantly higher incidence of VTE compared to pregnancies without this complication. The incidence rate was 448.8 per 1000 patient-years for women with preeclampsia, compared to 309.6 per 1000 patient-years for those without. Adjusted hazard ratios further underscored this risk, indicating a 43% increase in the likelihood of VTE for women with preeclampsia.
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