Pregnant patients with TA at increased risk for adverse pregnancy outcomes
A recent study published in the Nature Scientific Reports found that women with Takayasu arteritis (TA) have increased risk of adverse pregnancy outcomes than general population.
Takayasu arteritis (large vessel vasculitis) is a rare autoimmune disease that affects the aorta and its branches, mainly in young women. Due to its systemic nature, pregnancies in TA patients are at high risk of adverse outcomes. There is limited information on the incidence of adverse pregnancy events in these patients. So, Styliani Partalidou and team undertook this study to evaluate the prevalence of adverse pregnancy outcomes, including miscarriage, hypertension, and pre-eclampsia, in women with TA. The researchers conducted a systematic review and meta-analysis of 27 studies, which included a total of 825 pregnancies in TA patients.
The key findings of the study were:
The prevalence of adverse pregnancy outcomes in TA patients was high.
The occurrence of miscarriage was 16%, hypertension was 37%, and pre-eclampsia was 14%, which in turn indicate that TA patients have a higher risk of adverse pregnancy outcomes than the general population.
Also, close monitoring is essential for pregnant women with TA to ensure the best possible outcomes.
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