Relugolix Combination Therapy Improves Pain, Functioning, and Quality of Life in Women with Endometriosis: Study
USA: Recent research published in the journal Fertility and Sterility has highlighted the significant benefits of relugolix combination therapy (CT) in treating endometriosis-associated pain, demonstrating its ability to improve functioning and quality of life (QoL) for affected women.
The findings of a new study extended the evaluation of relugolix CT up to 104 weeks, showcasing its potential to provide sustained relief from the pain associated with endometriosis. The study showed that women receiving relugolix CT experienced a significant reduction in pain symptoms, including dysmenorrhea (painful periods), non-menstrual pelvic pain (NMPP), and dyspareunia (pain during intercourse). This marks a substantial improvement in managing one of the most debilitating aspects of endometriosis.
Endometriosis is a chronic condition where tissue similar to the lining of the uterus grows outside the uterus, causing severe pain, irregular bleeding, and potential fertility issues. For many women, endometriosis-associated pain severely impacts daily functioning and overall well-being.
Against the above background, Sawsan As-Sanie, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, and colleagues aimed to evaluate the impact of relugolix combination therapy (relugolix CT; 40 mg relugolix, 1 mg estradiol, and 0.5 mg norethisterone acetate) over up to two years in the SPIRIT long-term extension study. They focused on its effects on functioning and health-related quality of life (QoL), as measured by the Endometriosis Health Profile (EHP)-30 questionnaire, and examined how changes in QoL domains correlated with improvements in dysmenorrhea and nonmenstrual pelvic pain.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.