Spontaneous abortion tied to increased gestational diabetes risk in future pregnancies: Study

China: A previous history of spontaneous abortion (SAB) was linked to an elevated risk of gestational diabetes (GD) in subsequent pregnancies. More study is needed to elucidate this connection and investigate the probable molecular processes underlying it, says an article published in the Journal of American Medical Association.

Gestational diabetes is among the most prevalent and serious pregnancy problems. Identifying pregnant women who are at high risk of gestational diabetes is critical for early prevention and management. Yan Zhao and colleagues undertook this investigation to determine if a history of spontaneous or induced abortion is connected with an increased risk of GD in subsequent pregnancies.

A tertiary hospital in Shanghai, China, undertook this retrospective cohort research. Pregnant women who received standard prenatal care from January 2014 to December 2019 were included in the study. From December 2020 through June 2021, data were analyzed. Maternal abortion history, including SAB and induced abortion, was obtained from medical records. Where GD was diagnosed with a 75-g diagnostic oral glucose tolerance test, the main outcomes and measures were assessed. A multivariable-adjusted log-binomial analysis was performed to determine the relative risks (RRs) and 95% confidence intervals (CIs) of GD linked with abortion history.