WHO Releases Updates Guidelines on Oxytocin Use for Postpartum Hemorrhage Prevention

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2024-12-20 14:45 GMT | Update On 2024-12-20 14:46 GMT

USA: The World Health Organization (WHO) has issued updated guidelines on the administration of oxytocin for the prevention of postpartum hemorrhage (PPH) following vaginal birth. PPH, defined as a blood loss of 500 mL or more within 24 hours after delivery, remains a leading cause of maternal mortality, particularly in low-income countries. These recommendations aim to enhance care during childbirth and support global health goals, including reducing maternal mortality to fewer than 70 per 100,000 live births by 2030.

The WHO recommends administering 10 international units (IU) of oxytocin intramuscularly or intravenously to prevent PPH in all vaginal births. In cases where women already have intravenous (IV) access, slow IV administration is preferred due to its superior health outcomes. Evidence indicates that IV oxytocin reduces the risk of PPH, severe PPH, the need for blood transfusions, and severe maternal complications compared to intramuscular (IM) administration.

"Oxytocin (10 international units [IU]) is recommended for preventing postpartum hemorrhage in all births, administered either intramuscularly or intravenously. For women undergoing vaginal delivery who already have intravenous access, the slow intravenous administration of 10 IU oxytocin is preferred over intramuscular administration," the WHO stated.

However, the WHO cautions against routine IV access solely for oxytocin administration, emphasizing its feasibility and the potential impact on resources, health equity, and maternal comfort. The guideline advises that IV oxytocin be administered slowly to mitigate potential safety risks, such as hemodynamic changes, associated with rapid IV bolus injections.

While both IV and IM routes effectively prevent PPH, the updated recommendation underscores the importance of tailoring practices to specific clinical contexts. For example, in settings where IV access is not routinely available, IM oxytocin remains a reliable option.

The updated guidance reflects the WHO’s rigorous review process, which includes systematic evidence assessments and consultations with global experts. These recommendations supersede those issued in the 2012 guideline on PPH prevention and address the latest evidence to guide healthcare providers, policy-makers, and program managers worldwide.

The WHO emphasizes that the effective prevention of PPH requires more than just clinical interventions; it involves addressing inequities in maternal health and ensuring the availability of skilled healthcare personnel, adequate resources, and evidence-based practices. By implementing these guidelines, the global community takes a crucial step toward improving maternal health outcomes and reducing disparities in care.

This latest update aligns with WHO’s broader mission to enhance maternal and perinatal health, ensuring that childbirth is safer for all women, regardless of their geographic or socioeconomic circumstances.

Reference:

WHO recommendation on routes of oxytocin administration for the prevention of postpartum haemorrhage after vaginal birth. Geneva: World Health Organization; 2020. Licence: CC BY-NC-SA 3.0 IGO.

Article Source : World Health Organization (WHO)

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Medha Baranwal

Comments Policy

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

WHO Releases Updates Guidelines on Oxytocin Use for Postpartum Hemorrhage Prevention

Similar News

Paths to Recovery: Study Examining Surgical Options for Non-Severe Cesarean Scar Defects

New Approach to Safe Deliveries: Enhancing Care for Low-Risk Childbirths Through Collaboration, study suggests

Inhaled Insulin Shows Promise as Safe Option for diabetes management in Pregnancy: Study

Beyond Scores: Study Enhancing Neonatal Outcomes through APGAR Analysis

WHO Calls for Inclusion of Pregnant and Lactating Women in TB Research, vaccine trials

WHO Leads Global Call to Include Pregnant, Lactating Women in TB Research

Midwives willing to adopt alternative labour positions if they trust their safety and effectiveness: Study

From Data to Action: Study Identifying Determinants of Short Birth Intervals