Computer-aided detection tied to higher detection rates of colorectal neoplasia: Lancet

The primary analysis comprised 50 randomized controlled studies with a total of 34 445 individuals. In all 50 investigations, HD white-light endoscopy was used as the control method. When compared to the control approach, the adenoma detection rate with CADe was 74% higher, 44% higher with chromoendoscopy, and 41% higher with enhanced mucosal visibility systems. Cross-comparisons of CADe with other imaging techniques revealed a substantial increase in the adenoma detection rate with CADe against enhanced mucosal visibility systems, as well as with CADe compared chromoendoscopy. As focused on large adenomas (10 mm), there was a substantial increase in detection only with CADe when compared to HD white-light endoscopy; CADe was regarded as the superior method for detection of large adenomas. Although no significant improvement in sessile serrated lesion detection rate was seen, CADe appeared to be the best method for detection of sessile serrated lesions. There was no statistically significant difference in withdrawal time between CADe and the other methods.

"CADe appears to have an advantage over other advanced endoscopy imaging techniques, such as chromoendoscopy or mucosal visualization tools, for increasing the detection of colorectal neoplasia," the authors wrote. "This supports wider incorporation of CADe technologies into community endoscopy services."

Reference:

Spadaccini M, Iannone A, Maselli R, et al. Computer-aided detection versus advanced imaging for detection of colorectal neoplasia: A systematic review and network meta-analysis. Lancet Gastroenterol Hepatol. Published online August 4, 2021.

doi:10.1016/S2468-1253(21)00215-6