Green tea, enterolactone and soy intake may improve survival in breast cancer patients
USA: A recent meta-analysis of observational studies showed significant risk reduction in outcomes after breast cancer with the intake of green tea, enterolactone, and soy. The findings were published online in JNCI Cancer Spectrum.
Novel findings of the study were the significant risk reduction with soy isoflavones for recurrence in estrogen receptor–positive survivors and the significant associations between enterolactone (ENL) and all-cause mortality and breast cancer–specific mortality for women with node-negative disease. Findings for the overall cohorts were otherwise consistent with those of previous meta-analyses examining high vs low intake
Previous studies have suggested improvement in outcomes following breast cancer with phytonutrient intakes. Still, the impact of postdiagnosis introduction versus established prediagnostic exposure and optimum doses has not been established. To fill this knowledge gap, M Diana van Die, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA, and colleagues aimed to inform patients, clinicians, researchers, and policymakers of the evidence from observational studies for lignans, soybean, green tea, and cruciferous vegetables, as well as their phytonutrients on breast cancer–specific mortality, breast cancer recurrence, and all-cause mortality, with a focus on the most effective dosage and time frame for consuming these exposures by conducting a systematic review and meta-analysis.
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