New imaging technique found effective for detection of gastric lymphomas
A new imaging technique for the detection of MALT lymphomas, malignant tumours of the lymphatic system, could probably save patients numerous gastroscopies.
A study group of MedUni Wien achieved a high imaging accuracy by way of PET/MR and by using a PET Tracer directed against a certain cell receptor.
The results are currently published in the top journal "Blood" of the American Society of Hematology.
Results show that [68Ga]Pentixafor PET/MR has a very high accuracy. For example, it demonstrated 97%accuracy in detecting the tumour compared to gastroscopy in patients with MALT lymphoma of the stomach after H. pylori treatment.
"If a sufficiently high CXCR4 expression is detected at the initial diagnosis of MALT lymphoma, the new imaging could replace repeated gastroscopies in the course of the disease in the future or at least increase the time intervals between gastroscopies," says study first author Marius Mayerhöfer, explaining the advantages for those affected.
The findings support an earlier publication by the research team (published in 2019 in the top journal Theranostics), which indicated high sensitivity of [68Ga]Pentixafor PET/MR for the detection of MALT lymphomas in various organs and tissues.
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