Ramiven: The only CDK4/6i that Delivers Proven and Deepening Protection After a 2-year Treatment Period

Written By :  Medical Dialogues Team
Published On 2025-11-28 06:45 GMT   |   Update On 2025-11-28 07:08 GMT
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In the video, Dr. Carlos Barrios, director and principal investigator of the Oncology Research Center at Hospital Sao Lucas and president of the Latin American Cooperative Oncology Group (LACOG) in Porto Alegre, Brazil, explains how Ramiven combined with endocrine therapy may improve outcomes for patients with node-positive, high-risk early breast cancer (EBC). He further notes that...

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In the video, Dr. Carlos Barrios, director and principal investigator of the Oncology Research Center at Hospital Sao Lucas and president of the Latin American Cooperative Oncology Group (LACOG) in Porto Alegre, Brazil, explains how Ramiven combined with endocrine therapy may improve outcomes for patients with node-positive, high-risk early breast cancer (EBC).

He further notes that two years of Ramiven combined with endocrine therapy, either an aromatase inhibitor or tamoxifen, provides lasting protection for node-positive, high-risk early breast cancer patients.1,2 

With Ramiven plus endocrine therapy, more patients remain free of metastatic disease than with endocrine therapy alone.1

About twice as many patients progressed to incurable metastatic disease on endocrine therapy alone compared with Ramiven plus endocrine therapy. The benefit is consistent in patients with 1–3 positive nodes with high-risk features and in those with 4 or more positive lymph nodes. Ramiven helps keep node-positive, high-risk early breast cancer patients on track, with benefits extending beyond the 2-year treatment period.1


References:

1. Rastogi P, et al. J Clin Oncol. 2024;42(9):987–93. 2. Ribociclib, Summary of Product Characteristics, April 2025. 3. Johnston SRD, et al. J Clin Oncol. 2020;38(34):3987–98. 4. Ramiven India Prescribing Information, Literature revised: 6 July 2023, Version Control No. PA008SPIN05 5. Freedman RA, et al. J Clin Oncol. 2024;42(18):2233–5. 6. Loibl S, etal. Ann Oncol. 2024;35(2):159–82. 7. Curigliano G, et al. Ann Oncol.2023;34(11):970–86.

 PP-AL-IN-1805 | 17/11/2025

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