Rapid test for detection of ovarian cancer developed
Researchers have found that Aberrant sugar structures can be used in early cancer diagnostics along with CA125 detection.
The CA125 antigen, a plasma membrane glycoprotein found in the tissues of the female reproductive tract, is commonly used for the detection of ovarian cancer but works poorly on its own in identifying early stage cancers. The cancer specificity can be improved significantly when CA125 detection is combined with targeting aberrant sugar structures in the tumour.
The goal of the research group led by Professor Kim Pettersson at the University of Turku, Finland, is to develop novel tests that use the detection of modified sugar structures from the cancer tissue. The recently published article describes how the research group developed this rapid and sensitive point-of-care diagnostic test that can detect ovarian cancer from the patient's blood sample.
With the easy-to-run and rapid test developed in the study, ovarian cancer can be more accurately detected from a blood sample in 30 minutes. The technologies of the Biotechnology unit at the Department of Biochemistry, as well as their expertise in label technology and rapid tests, were widely used in this study.
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