Regardless of Site, Newly Diagnosed Cancer Patients Are At Risk of CV Mortality
Cancer and cardiovascular (CV) disease share many risk factors, including smoking, lower socioeconomic status, and obesity. This suggests that patients with cancer constitute a high-risk population for CV disease. A recent study added further value and suggests that a new cancer diagnosis is associated with an increased risk for cardiovascular death and nonfatal morbidity. The study findings were published in the JACC: CardioOncology on March 15, 2022.
Patients with cancer and cancer survivors are at increased risk for incident heart failure, but there are conflicting data on the long-term risk for other cardiovascular events and how such risk may vary by cancer site. To further explore, Dr D. Ian Paterson and his team conducted a study to determine the impact of a new cancer diagnosis on the risk for fatal and nonfatal cardiovascular events.
Using administrative health care databases, the researchers conducted a population-based retrospective cohort study among 4,519,243 adults residing in Alberta, Canada, from April 2007 to December 2018. They compared the patients with new cancer diagnoses during the study period with those without cancer with respect to risk for subsequent cardiovascular events (cardiovascular mortality, myocardial infarction, stroke, heart failure, and pulmonary embolism) using time-to-event survival models after adjusting for sociodemographic data and comorbidities.
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