Anticoagulant, antiplatelet medication may prevent diabetic retinopathy in type 2 diabetes patients: Study
Taipei, Taiwan: Antiplatelet/anticoagulant (APAC) medications have a protective effect against the development of nonproliferative diabetic retinopathy (NPDR) in type 2 diabetes patients, a recent study has found. The authors wrote, "single-use of aspirin or dipyridamole may benefit diabetes patients for the prevention of nonproliferative diabetic retinopathy." The study appears in the journal BMC Ophthalmology.
Cheng-Li Lin, Management Office for Health Data, China Medical University, Taichung, Taiwan, and colleagues conducted the study with an aim to investigate whether antiplatelet/anticoagulant therapy can protect patients with type 2 diabetes mellitus from the development or progression of diabetic retinopathy (DR) in a retrospective cohort study.
The study used Longitudinal Health Insurance Database in Taiwan. It included a total of 73,964 patients with type 2 diabetes older than 20 years old. Hazard ration (HR) of non-proliferative DR (NPDR), proliferative DR (PDR), and diabetic macular edema (DME) were analyzed with APAC usage as a time-dependent covariate. In a multivariable model, age sex, comorbidities, and medicines were further adjusted. Contributions of respective APAC were investigated with sensitivity analysis.
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