Cataract surgery significantly improves cognition among elderly with mild cognitive impairment

Out of the 132 patients initially screened, 88 met the inclusion criteria. Among these patients, 39 were categorized into the dementia group, while 49 were classified in the MCI group. Notably, the MCI group showed significant improvement in MMSE scores from pre-surgery (25.65 ± 1.03) to post-surgery (27.08 ± 1.99) and MMSE-blind scores from pre-surgery (18.04 ± 1.14) to post-surgery (19.41 ± 2.01) (both p < 0.001).

The study findings indicated a noteworthy enhancement in cognitive function following cataract surgery, especially in patients with MCI compared to those with dementia. Statistical analysis revealed a substantial likelihood of improvement in cognitive function in the MCI group post-surgery when compared to the dementia group (odds ratio, 2.85; 95% confidence interval, 1.02–7.97; p = 0.046).

Importantly, the study suggests that the extent of cognitive improvement post-surgery might be closely linked to the patient's preoperative cognitive state.

These findings provide promising insights into the potential cognitive benefits of cataract surgery, particularly for individuals experiencing mild cognitive impairment. However, further research is warranted to comprehensively understand the underlying mechanisms and the long-term impact of cataract surgery on cognitive function in the elderly population.

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