Combining Cyclosporine Eye Drops with Punctoplasty Improves Outcomes in Acquired Punctal Stenosis: Study Finds
Turkey: A recent study has evaluated the impact of cyclosporine A (CsA) eye drops on the success of punctoplasty in patients with acquired punctal stenosis (APS). This condition can cause excessive tearing and ocular discomfort. The findings revealed that combining CsA 0.05% eye drops with punctoplasty significantly improved treatment outcomes in APS.
"At the six-month follow-up, the highest functional success rate was observed in the CsA plus punctoplasty group (88%), compared to 79% with punctoplasty alone and 69% with CsA alone. The combined approach also achieved an anatomical success rate of 90%, indicating its effectiveness in enhancing postoperative recovery and long-term outcomes," the researchers reported in Current Eye Research.
Acquired punctal stenosis is characterized by narrowing the tear drainage openings, leading to chronic epiphora (excessive tearing) and discomfort. Punctoplasty, a minor surgical procedure that enlarges the punctal opening, is a common treatment approach. However, inflammation often contributes to APS, raising interest in anti-inflammatory treatments such as CsA, a topical immunomodulator known for its anti-inflammatory effects in ocular surface diseases.
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