Early intervention for idiopathic full thickness macular holes provide better visual outcomes: Study
In a new study conducted by Declan C. Murphy and team, it was shown that in patients undergoing surgery for idiopathic full thickness macular holes (iFTMH), symptom duration was independently correlated with both structural and visual results. The findings of this study were published in Ophthalmology Journal.
IFTMH has an incidence of up to 0.5% and are visually incapacitating. Best corrected visual acuity (BCVA) drops to 20/200 when left untreated. Surgery can restore eyesight and repair holes. Although the impact of symptom duration on surgical results is unknown. Therefore, using individual participant data (IPD) research of randomized controlled trials, this study sought to establish the impact of symptom duration on outcomes in patients having surgery for iFTMH. Primary iFTMH completion and post-operative best corrected visual acuity were the outcomes evaluated.
For this study, in people with iFTMH who had vitrectomy with gas tamponade, a systematic review found eligible RCTs in which symptom duration, primary iFTMH closure, and post-operative BCVA were noted. The search for publications published between 2000 and 2020 was conducted using bibliographic databases.
The key findings of this review were:
1. There were 20 qualifying RCTs found. Data from all research was sought, and 12 studies, totaling 940 eyes, provided the data.
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