Female hormone therapy not linked to retinal vascular occlusion; JAMA Ophthalmology
According to a recent study findings, filling a prescription for Female Hormone Therapy (FHT), and presumably taking FHT, does not increase the risk of Retinal Vascular Occlusion (RAO) or RVO.
The interesting findings have been published in JAMA Ophthalmology.
Female hormone therapy (FHT) includes oral contraceptive pills (OCPs) in women of reproductive age and hormone therapy in postmenopausal women. It is well documented that Oral contraceptives are associated with cardiovascular disease, ischemic stroke, venous thromboembolic disease, and breast cancer. Retinal vascular occlusions share the same risk factors as cardiovascular and cerebrovascular disease. To date, numerous case reports have associated oral estrogen use with developing RVO or RAO.
To have a in-depth understanding on this topic, researchers undertook a study to determine whether filling a prescription of female hormone therapy (FHT) is associated with an increased risk of retinal artery occlusion (RAO) or retinal vein occlusions (RVO).
For the study design,a multiple-cohort study was conducted using an administrative claims insurance database comparing women who filled a prescription for FHT with matched control individuals. Exclusion occurred for those enrolled for less than 2 years in the plan, with no prior ophthalmologic examination, with a history of a RAO/RVO, with systemic diseases/medications that affected estrogen levels, or a disease associated with an increased risk for thromboembolism.
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