For asymptomatic patients with primary angle-closure suspect, simple eye examination may predict glaucoma
Understanding the risk factors and developing prediction models for the progression from Primary Angle Closure Suspect (PACS) to primary angle closure (PAC) is crucial for effective management. PACS eyes' progression to PAC remains understudied in long-term investigations. Identifying reliable predictors can aid clinicians in assessing the risk of progression and implementing targeted interventions for better patient outcomes.
A recent study was published in JAMA Ophthalmology by Yixiong Yuan and colleagues. A 14-year longitudinal cohort study, based on the Zhongshan Angle Closure Prevention trial, explores baseline predictors to enhance the customization of PACS management. The study involved 377 eyes from the Zhongshan Angle Closure Prevention trial, focusing on untreated eyes with PACS. Baseline examinations included tonometry, ultrasound A-scan biometry, and anterior segment optical coherence tomography (AS-OCT) under light and dark conditions. Logistic regression models were constructed based on baseline covariates to predict the 14-year risk of progression from PACS to PAC.
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