High rate of concurrent retinal non perfusion encountered in Pediatric patients with optic nerve hypoplasia

in 7 eyes (63.63%), moderate severity in 2 eyes (18.18%), severe severity in one eye

(9.09%), and extreme severity in one eye (9.09%).

5. In eight eyes (72.72%), there was proof of complete retinal nonperfusion.

6. At the time of diagnosis, two patients (18.18%) had concomitant retinal detachments that were judged inoperable. Researchers witnessed every case without taking any action. During follow-up, no patient was seen to have any problems.

This discovery is not entirely understood, and the association between optic nerve hypoplasia and retinal disorders including familial exudative vitreoretinopathy as well as its connection with septo-optic dysplasia has not yet been thoroughly defined.

In conclusion, peripheral retinal nonperfusion, which is frequent in children with optic nerve hypoplasia, can be challenging to identify without anesthetic testing or fluorescein angiography. FA is a useful technique to identify peripheral nonperfusion in these circumstances. Retinal Results can be faint in certain situations, and in children with poor imaging conducted without a physical examination under anesthesia, they could not be discernible at all.

Reference: 

da Cruz, N. F. S., Sengillo, J. D., Fan, J., Negron, C. I., Felder, M. B., & Berrocal, A. M. (2023). Peripheral Retinal Nonperfusion in Pediatric Patients with Optic Disc Hypoplasia. In American Journal of Ophthalmology. Elsevier BV. https://doi.org/10.1016/j.ajo.2023.03.024