Higher intake of vitamin B1 associated with lower risk of age-related macular degeneration
Vitamin B1, called thiamine, is a water-soluble, colourless, odourless, and slightly bitter vitamin necessary for all living organisms. It is a cofactor for various enzymes involved in metabolic processes, mainly carbohydrate and amino acid metabolism. Since humans cannot produce their own vitamin B1, it must be obtained through food sources. Deficiency in vitamin B1 has been linked to polyneuritis, Alzheimer's disease, colon cancer, beriberi, Wernicke's encephalopathy, paralysis, and cardiac failure.
A study published in Ophthalmic Research found a negative correlation (inverse association) between vitamin B1 intake and late age-related macular degeneration in the US. According to them, more randomized clinical trials are needed to investigate the relationship.
AMD, a leading cause of permanent blindness globally, is investigated for its correlation with vitamin B1 intake in a US representative sample as part of the current study.
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