Immunomodulatory Therapy bests Steroids in Multifocal Choroiditis Patients with Choroidal Neovascularization
Multifocal Choroiditis (MFC) patients with inflammatory choroidal neovascularization (iCNV) face challenges in visual and treatment outcomes. A recently published study delves into the effectiveness of Immunomodulatory Therapy (IMT) compared to an approach using steroids as needed, shedding light on visual and treatment outcomes. This study was published in the American Journal of Ophthalmology by Matteo Airaldi and colleagues.
Dividing MFC patients into IMT and steroid groups, outcomes were compared over a 2-year follow-up. Parameters included visual acuity (VA), anti-Vascular Endothelial Growth Factor injections (IVIs), and iCNV reactivations. The influence of MFC-related inflammation on iCNV reactivation risk was also examined. Conducted as a multicenter retrospective matched cohort study, the research scrutinized patients with MFC and iCNV. The two groups, IMT and "steroids as needed," were meticulously matched based on the time from diagnosis to the initiation of systemic treatment.
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