Inflammatory Bowel Disease associated with Eye related issues

A recent study uncovered a significant connection between Inflammatory Bowel Disease (IBD) and eye-related health issues. This study published in BMC Ophthalmology delved into the temporal relationship between IBD, Dry Eye Disease (DED), and corneal surface damage, and found the need for increased awareness and clinical strategies for those at risk.

The research included 54,293 matched pairs of subjects. Results demonstrated a higher incidence of DED in individuals with IBD, with a rate of 8.18 per 1000 person-years, compared to 5.42 in the non-IBD group. After adjusting for various factors, including confounders, the study established statistically significant associations between IBD and DED, along with its subtypes.

Specifically, the analysis revealed that individuals with IBD faced a 43% increased risk of DED compared to those without the condition. Notably, this risk extended to both Sjögren’s syndrome-related and non-Sjögren’s syndrome-related subtypes of DED, with respective increased risks of 67% and 38%. The research also unearthed a 13% increased risk of corneal surface damage among IBD patients when compared to the control group.

The study found that factors such as age, sex, and monthly insurance premiums also played a role in the likelihood of corneal surface damage. Notably, age and insurance premium levels were independent factors influencing this risk, while gender differences were observed.

These findings are crucial in understanding the broader health implications of IBD and emphasize the importance of comprehensive patient care. With IBD being identified as an independent risk factor for DED and ocular surface damage, it's clear that proactive clinical strategies are needed to mitigate potential visual impairment and losses in this vulnerable patient group.

This study highlights the importance of interdisciplinary approaches to patient care. It underscores the need for healthcare providers to consider the broader health implications of conditions like IBD and to work collaboratively to develop strategies for early detection and management of associated health issues, such as eye complications.

Source:

Ko, Y.-T., Wu, Y.-M., Wu, H.-L., Lai, S.-C., Dai, Y.-X., Chen, T.-J., Cherng, Y.-G., Tai, Y.-H., & Kao, C.-Y. (2023). Inflammatory bowel disease and the associated risk of dry eye and ocular surface injury: a nationwide matched cohort study. In BMC Ophthalmology (Vol. 23, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12886-023-03165-z