Intravitreal anti-VEGF treatment for neovascular AMD tied to glaucoma progression
A study published in the Acta Ophthalmologica has concluded that Neovascular age-related macular degeneration (nAMD) coexists with glaucoma in the same eye. This co-existence is similar to the general population's prevalence of two age-related diseases.
Age-related macular degeneration and glaucoma cause permanent visual impairment in developed countries, including Finland. Intravitreal injections with anti-vascular endothelial growth factors (anti-VEGF) are the primary therapeutic approach for nAMD.
The literature mentions mixed results on glaucoma progression during anti-VEGF treatment for nAMD. It may also lead to an increased risk for glaucoma surgery.
Dr Inka Pirinen and colleagues investigated,
How often do glaucoma and nAMD occur in the same patient, and whether glaucoma progression is faster on treatment with intravitreal anti-VEGF used for managing nAMD?
Tays Eye Center's patient medical records of 6314 glaucomas and 2166 nAMD patients were available. The researchers compared changes in visual fields (mean deviation [MD], dB/year), IOP (mmHg/year) and fundus photographs (progression, yes/no) with and without anti-VEGF treatment for nAMD and ≥ 1-year follow-up.
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