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Micropulse Transscleral Laser Therapy effective for silicone oil-induced glaucoma

Written By :  Dr.Niharika Harsha B
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2022-09-13 00:00 GMT   |   Update On 2022-09-13 06:39 GMT

CAPTION

Researchers have developed a potential new treatment for the eye disease glaucoma that could replace daily eye drops and surgery with a twice-a-year injection to control the buildup of pressure in the eye.

CREDIT

Rob Felt, Georgia Tech

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New research found that Micro pulse transscleral laser therapy (MP-TLT) is successful in reducing the Intraocular pressure (IOP) in uncontrolled silicone oil–induced glaucoma (SOG). The study was published in the Journal of Glaucoma.  

Silicone oil has been used as an adjunct for internal tamponade in the management of complicated retinal detachment which is leading to the development of secondary glaucoma called silicone oil-induced glaucoma. Micropulse transscleral laser therapy is a non-invasive laser procedure that is used to reduce intraocular pressure in glaucoma. Researchers from Tunisia studied a prospective case series of 33 eyes to assess the efficiency and safety of MP-TLT in the management of SOG. 

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Participants with uncontrolled SOG were enrolled at the Department of Ophthalmology of Mohamed Taher Maamouri Hospital, Nabeul, Tunisia, and were treated with MP-TLT using the IRIDEX Cyclo G6 Glaucoma Laser System with the MicroPulse P3 fiberoptic handheld probe. They also underwent a complete ophthalmologic examination during the 12-month follow-up period.  

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Results:

  • 33 eyes of 33 patients with SOG were included in the study with a mean age was 50.39 years old.
  • Out of these, Silicone oil tamponade was indicated for complicated rhegmatogenous retinal detachment in 22 cases, diabetic tractional retinal detachment in 10 cases, and posttraumatic retinal detachment in 1 case.
  • Silicone oil was already removed before the procedure in 23 eyes.
  • Silicone oil tamponade duration varied between 3 and 26 months.
  • Intraocular pressure (IOP) measurements at enrollment; days 1, 7, and 15; and months 1, 3, 6, and 12 were respectively 37.94±13.61, 19.03±10.98, 16.5±6.17, 19.45±9.73, 19.27±8.33, 19.39±9.52, 19.97±10.03, and 19.7±9.58 mm Hg.
  • IOP lowering was 45.38% at 6 months and 45% at 12 months.
  • There was a 93.93% of success rate at 6 months and remained stable at 12 months.
  • There was no phthisis bulbi nor prolonged inflammation or any other type of major side effects observed.
  • No difference was noticed in IOP lowering between patients with silicone oil or those after silicone oil removal (P=0.99). 
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Thus, the researchers concluded that MP-TLT was safe and effectively lowered IOP in uncontrolled SOG.

For further reading, click here: 10.1097/IJG.0000000000002051 

Zbiba W, Sayadi S, Kharrat M, Daoued M. Efficacy and Safety of Micropulse Transscleral Laser Therapy in Silicone Oil-induced Glaucoma. J Glaucoma. 2022;31(8):689-693. 

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Article Source : Journal Of Glaucoma

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Dr.Niharika Harsha B

Dr.Niharika Harsha B (BDS,MDS) completed her BDS from Govt Dental College, Hyderabad and MDS from Dr.NTR University of health sciences(Now Kaloji Rao University). She has 4 years of private dental practice and worked for 2 years as Consultant Oral Radiologist at a Dental Imaging Centre in Hyderabad. She worked as Research Assistant and scientific writer in the development of Oral Anti cancer screening device with her seniors. She has a deep intriguing wish in writing highly engaging, captivating and informative medical content for a wider audience. She can be contacted at editorial@medicaldialogues.in.

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