Netarsudil and latanoprost combo useful fixed dose option for open-angle glaucoma and IOP: Study
A recent study published in the Graefe's Archive for Clinical and Experimental Ophthalmology compared the effectiveness and safety of two fixed-dose combination (FDC) ophthalmic solutions for treating open-angle glaucoma (OAG) and ocular hypertension (OHT). This study evaluated the efficacy of the FDC of netarsudil 0.02%/latanoprost 0.005% (NET/LAT; Roclanda®) against bimatoprost 0.03%/timolol maleate 0.5% (BIM/TIM; Ganfort®).
Over a 6-month period, the MERCURY-3 study included patients over 18 years with OAG or OHT that was insufficiently controlled by topical medication. The efficacy and safety of NET/LAT and BIM/TIM were assessed at various intervals throughout the study.
The results indicated that NET/LAT was non-inferior to BIM/TIM in reducing intraocular pressure (IOP), with no statistically significant difference between the two treatments. Both treatments demonstrated a mean diurnal IOP ranging from 15.2 to 15.6 mmHg, where NET/LAT showed comparable efficacy to BIM/TIM. Also, no treatment-related adverse events were observed, with most adverse events being mild to moderate in severity.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.