NSAID effective in reducing pseudophakic cystoid macular edema post-operatively: Study
A new study published in the International Journal of Retina and Vitreous showed that nonsteroidal anti-inflammatory drugs (NSAIDs), either by themselves or in conjunction with steroids, have demonstrated effectiveness in lowering the incidence of pseudophakic cystoid macular edema (PCME) following surgery.
Optical coherence tomography (OCT) analysis of cystoid macular edema (CME) which is a well-known surgical consequence, reveals central subfield macular thickness, cystic hyporeflective lesions, and subfoveal fluid. CME that after cataract surgery is known as PCME. It is thought to be the most frequent reason for vision decline following surgery. The main theory for PCME is mechanical manipulation linked to the release of inflammatory mediators.
In order to successfully lower the incidence of PCME, no standardized preventive procedure has been developed as of yet. So, Abdullah Alqahtani and his colleagues evaluated the safety and effectiveness of corticosteroids and nonsteroidal anti-inflammatory drops in preventing PCME. This study included randomized controlled trials (RCTs) that examined the effectiveness of NSAID against placebo, steroid, or NSAID + steroid against placebo which indicated the prevalence of macular thickness, PCME, and best-corrected visual acuity.
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