OCTA helps predict optical complications in Diabetic Retinopathy
A recent study published in Ophthalmology Retina Journal suggest that optical coherence tomography angiography (OCTA) can predict the development of clinical outcomes in eyes with non-proliferative diabetic retinopathy (NPDR), and could also be useful in guiding early intervention and preventing visual impairment.
Diabetic retinopathy (DR) is a chronic and progressive ocular disease that affects people with diabetes, and is a leading cause of blindness worldwide. Early detection and management of DR is critical for preventing visual impairment and blindness. In recent years, the development of OCTA has allowed for the evaluation of retinal blood flow and the identification of capillary nonperfusion in the retina. The study by Janice Ong and team was aimed to evaluate the ability of capillary nonperfusion parameters on OCTA to predict the development of clinically significant outcomes in eyes with NPDR.
In this prospective longitudinal observational study, a total of 59 patients with treatment-naive moderate to severe referable NPDR were imaged with OCTA at baseline and followed for 1 year. Two OCTA capillary nonperfusion metrics, vessel density (VD) and geometric perfusion deficits (GPDs), in the superficial capillary plexus, middle capillary plexus, and deep capillary plexus were evaluated.
The key highlights of this study were:
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