Optic neuritis linked to inflammatory response in patients with fibromyalgia

Results:

• The fibromyalgia and non-fibromyalgia groups included 479,892 and 479,892 participants, respectively.

• The incidence rate of optic neuritis was 35.65/100000 person-years in the fibromyalgia group; the HR was significantly higher in the fibromyalgia group than in the non-fibromyalgia group

• The mean interval between the onset of fibromyalgia and incident optic neuritis was 2.4 ± 1.8 years.

• The risk increased significantly in men between 60-79 years age group and in women between 20-39 years age group

Researchers quantified the risk of optic neuritis through a long-term follow-up, which could contribute to understanding the pathophysiology and estimating the general healthcare burden associated with FM in a practical setting. Great attention should be paid to its risk in older men and younger women.

Reference:

Cho HR, Lee GK, Lee JY. Increased risk of optic neuritis in patients with Fibromyalgia: nationwide population-based cohort study in South Korea. Am J Ophthalmol. 2023 Aug 25:S0002-9394(23)00343-4. doi: 10.1016/j.ajo.2023.08.015. Epub ahead of print. PMID: 37634609.

Keywords:

Optic neuritis, linked, inflammatory, response, patients, fibromyalgia, Cho HR, Lee GK, Lee JY, American Journal of Ophthalmology