Perceptual learning promising therapy for progressive keratoconus patients intolerant to contact lenses: Study
CAPTION
Rose-tinted contact lenses (about 10 mm in diameter) containing gold nanoparticles filter out problematic colors for people with red-green color blindness.
CREDIT
Adapted from ACS Nano 2021, DOI: 10.1021/acsnano.0c09657
Researchers have recently reported improvement of vision in patients with keratoconus (KC) even if spectacle correction was insufficient. Researchers have discovered that perceptual learning (PL) significantly improves the vision of patients with keratoconus, even when spectacle correction fails to correct vision. A recent randomized, double-blind clinical study has revealed that PL enhances the visual acuity not only of non-progressive patients with KC, but retains these improvements months after the end of treatment. The study was published in the American Journal of Ophthalmology by Xiang T. and colleagues.
This is a randomized, double-masked clinical study of 35 non-progressive KC patients, at least 9 years of age. All patients had unsatisfied spectacle-corrected visual acuity and were intolerant to contact lenses. Patients must have best spectacle-corrected distance visual acuity (CDVA) ranging from 0 to 1.0 logMAR (from Snellen visual acuity of 20/20 to 20/200).
Participants were divided into one of two groups: the PL group, who received perceptual learning training, and a control group who received placebo training for 3 months. Different visual outcomes such as CDVA, contrast sensitivity function (CSF), stereo acuity, and visual functioning and quality of life were measured on initiation of the trial (baseline) and at the end of 3 months post-training and at 6 months follow-up post-trial initiation.
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