Prophylactic cyclosporine eye drops reduce ocular inflammation after cataract surgery, reveals study
A recent study published in the recent issue of Cornea journal highlighted the significant rates of dissatisfaction following cataract surgery that pointed ocular surface discomfort as a primary cause. The study indicated that 20% to 35% of patients experienced dissatisfaction post-surgery due to this issue. This study investigated the role of age-related parainflammation in this discomfort and explored preventive measures through immune-modulating prophylactic management.
The prospective, randomized, open-label and unmasked clinical trial included a total of 100 patients who were diagnosed with cataracts. These patients underwent phacoemulsification surgery which is a common procedure to treat cataracts. The participants were divided into four groups of 25 patients; the patients in Group A had patients under 65 years old who received surgery only, the Group B included patients over 75 years old who received surgery only, the Group C had patients over 75 years old who used cyclosporine A 0.1% cationic emulsion (CE) eye drops twice daily for 30 days before surgery and in the Group D were the patients over 75 years old who used CE lubricating eye drops twice daily for 30 days before surgery. The patients were monitored for 90 days following surgery, with the primary outcome being postoperative ocular surface failure and the secondary outcome included the impact of prophylactic cyclosporine A 0.1% CE therapy on the ocular surface.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.