Tear secretions from lacrimal gland differ in normal versus dry eyes
Tears are necessary for maintaining the health of the ocular surface and normal vision. Several internal and external factors may affect tear film composition, integrity, and stability negatively, resulting in dry eye disease (DED). Recent research suggests that tear secretion significantly differs between evaporative dry eyes (EDE) aqueous deficient dry eye and dry eye in cicatrising conjunctivitis (CC). The research has been published in the journal BMJ Ophthalmology on February 17, 2021.
Dry eye disease (DED) is a multifactorial syndrome that can be caused by the alteration in the quality or quantity of the precorneal tear film. Studies suggest that between 5% and 50% of the adult population have symptoms of dry eye disease, and the condition is more common in Asian populations, especially in females. Evaporative dry eye, a condition affecting the meibomian glands, is one of the most common underlying causes of dry eye. Nearly 90% of people diagnosed with evaporative dry eye have MGD! However, the variation in the secretory status of the main lacrimal gland in dry eyes and normal eyes remains unclear. Therefore, researchers of the LV Prasad Eye Institute, Hyderabad, India conducted a study to investigate the secretory status of the main lacrimal gland in healthy and dry eye disease (DED) via fluorescein-assisted direct assessment of tear secretion from the palpebral lobes.
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